Adipose-Derived Stem Cells In Cosmetic Surgery: Ready For Prime Time?

Are adipose-derived stem cells in cosmetic surgery ready for prime time use in your cosmetic practice?

Google “aesthetic stem cell treatments” and you will be greeted with a panoply of therapeutic offerings ranging from mundane to fantastic. Injecting your own adipose derived stem cells can lift your face, tighten your skin, enlarged your breast, slow the ageing process and even put some zip in your libido if injected into anatomically correct nether regions. Cosmeceutical manufacturers are even putting non-viable stem cells into facial creams hoping to knock 10 years off your visage. These marketing claims have captivated the public with the promise of a minimally invasive fountain of youth.

Adipose-derived stem cells are multipotent and possess the ability to differentiate into fat, bone, cartilage, nerves and pancreatic tissue.  They also secrete cytokines that are angiogenic, antioxidative and immunosuppressive. They release a whole host of growth factors that facilitate wound healing and tissue regeneration. Stem cells hold great clinical potential and offer considerable commercial possibilities.

We are all very enthusiastic about the promise and potential offered by the emerging field of adipose- derived stem cell science. Encouraging data from hundreds of ongoing international trials support a bright future for aesthetic and regenerative applications and real progress has been made in developing methodologies and protocols for every day clinical use. Yet many are advising caution.

A recent review in Plastic and Reconstructive Surgery notes that there is considerable uncertainty about the true clinical potential of adipose-derived stem cells and too much remains unknown about their fundable biology to be used safely and reliably. There are several contradictory studies about whether these cells promote or repress cancer growth. There are no standard protocols yet developed for adipose-derived stem cell applications. We still are unsure of the number of cells required per treatment or how many treatments are needed to achieve a desired clinical outcome predictably. In short, we are not quite sure what we are doing yet with adipose-derived stem cells despite the encouraging science and our best intentions.

A lot remains unknown about how to effectively and safely use this new technology. To market aesthetic stem cell procedures outside of clinical trials to the public seems a bit deceptive considering the current state of the art. What do you think??

The Next Frontier: Stem Cell Enhanced Treatments

What was once considered and debated as a highly controversial topic, stem cells are being looked at in a completely different light.

We've always known that the use of stem cells were the cutting edge of medical science, but only now has the non-aesthetic arena begun to recognize and promote to the consumer the advantages stem cells have in the aesthetic industry.

In the Northeast Winter-Spring edition of New Beauty Magazine, the use of fat-derived stem cells is discussed in terms our patients and future patients can understand. The article states that plastic surgeons long discovered that fat harvested from liposuction procedures contain a vast amount of stem cells. And, while this was commonly known by many, exactly how to extract those stem cells and apply them is the one controversial factor faced by practitioners. The success of stem cell transfer is highly dependent on the techniques use for harvesting and processing, and other additives applied such as epithelial cells and growth factors. In the article Dr. Renato Calabria states "it's not as easy as just taking some fat and putting it where it's needed. This is a multistep procedure that is technique-dependent."

Regardless, physicians are embracing this fountain of youth and are researching and experimenting various techniques and applications to promote fuller breasts and buttocks, smoother skin by reducing pore size, improved skin tone and clarity, and stem-cell enriched fat transfer face lifts to name a few, and consumers are beginning to seek out those physicians who are pioneering the practice.

If this is not a band wagon you are contemplating jumping on, it definitely should be an area of aesthetics you will want to follow. As the word is now reaching consumers, ten-to-one they will be presenting you with questions.

Paula D. Young RN runs internal operations and training at Young Medical Spa and is the author of the Medical Spa Aesthetics Course, Study Guide, and Advanced IPL & Laser Training course for medical estheticians and laser technicians.

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Plastic Surgery Face Lift.. Or Stem Cells From Korea?

The same company in Korea that's cloning dogs and cats is now offering anti-aging treatemtns that are being touted as a delaying tactic for plastic surgery and face lifts:

Those who view aging as an ugly inconvenience usually turn to plastic surgery to nip and tuck their troubles away. Little do they know the answer for reversing the aging process might be found in their own stomachs.

Run in conjunction with the Beijing Tian Tan Puhua Hospital, which offers stem cell therapies to last-hope Parkinson’s and spinal cord injury patients, the RNL Puhua Plastic and Cosmetic Medical Center offers stem cell therapy for the face that may reverse the aging process using the patient’s own body matter.

Using a treatment developed by Korean company RNL Bio—the same company that clones dogs and sells them on the international market for upwards of USD$150,000—the Puhua Center offers non-invasive beauty treatment alongside traditional plastic surgery staples like liposuction, face peels and eye tucks.

For a cool ¥28,000, patients can have fat cells removed from their abdomens using a needle and local anesthetic. Two weeks later, after doctors have grown a crop of stem cells from the collected fat cells, patients return to have doctors inject the stem cells into their faces in a series of shots that plump out skin, erase wrinkles and generally take a decade off your appearance, says Ingela Palomäki, a former Beijing Tian Tan Puhua Hospital marketing representative and current director of Fortune Cookie, a stem cell product import/export company. Included in the price is a stem-cell top-up six months later. Patients can also have their stem cells stored at the clinic for ¥1,500 per year. Stem cells have a shelf life of about 15 years. The clinic is currently the only place in the world offering the therapy, Palomäki says.

RNL Bio flew in aging South Korean celebrity Kyung-gyu Lee for a test-run of the treatment at the clinic’s inauguration less than half a year ago.

“Koreans are flocking here by the busloads for the treatment,” Palomäki says. “It’s buying time.”

Because the treatment uses the patient’s own cells, there is no risk of the body rejecting the injections, she points out. The only concern is that the stem cells could copy cancer cells in the body—so cancer patients and survivors will want to take a pass.

While the U.S. and other countries weigh the benefits of stem cell therapies, many patients from abroad are already coming to Beijing for therapies they hope might make them forever young.

This use of technology solutionos around bio-engineering and stem cells could well percipitate a break through. Nanotechnology is an other area that offers the promise of using a nonsurgical medical technology in lieu of traditional plastic surgery.

Thermage and Botox are examples of technology that sprang from other areas of medicine in just this way.