From NewScientist.com: Cool down live longer.
Researchers have found that lowering the body temperature of mice by just 0.5°C extends their lifespan by around 15%. In the future, people might be able to take a drug to achieve a similar effect on body temperature and enjoy a longer life, they say.
The only previously proven method of significantly increasing the lifespan of an animal has been through a restricted calorie diet.
...in the future people might be able to take a drug that specifically targets the preoptic “thermostat” area in their brains to trick the body into cooling down slightly. Coming up with such a drug “will be very challenging”, but he hopes it would allow people to live longer without cutting back on the calories.